Lipoic Acid Prevents Renal Dysfunction in Experimental Diabetes
نویسندگان
چکیده
منابع مشابه
Ensete superbum ameliorates renal dysfunction in experimental diabetes mellitus
Objective(s):Hyperglycemia mediated oxidative stress plays a key role in the pathogenesis of diabetic complications like nephropathy. In the present study, we evaluated the effect of ethanolic extract of Ensete superbum seeds (ESSE) on renal dysfunction and oxidative stress in streptozotocin-induced diabetic rats. Materials and Methods:Glucose, HbA1c, total protein, albumin, renal function mar...
متن کاملensete superbum ameliorates renal dysfunction in experimental diabetes mellitus
objective(s):hyperglycemia mediated oxidative stress plays a key role in the pathogenesis of diabetic complications like nephropathy. in the present study, we evaluated the effect of ethanolic extract of ensete superbum seeds (esse) on renal dysfunction and oxidative stress in streptozotocin-induced diabetic rats. materials and methods:glucose, hba1c, total protein, albumin, renal function mark...
متن کامل-Lipoic Acid Prevents Endothelial Dysfunction in Obese Rats via Activation of AMP-Activated Protein Kinase
Min Han, Min-Seon Kim, Inho Jo, Goo Taeg Oh, In-Sun Park, Jang Hyun Youn, Seong-Wook Woo Je Lee, In Kyu Lee, Hyoun Sik Kim, Yun Mi Kim, Eun Hee Koh, Jong Chul Won, Sung AMP-Activated Protein Kinase -Lipoic Acid Prevents Endothelial Dysfunction in Obese Rats via Activation of α Print ISSN: 1079-5642. Online ISSN: 1524-4636 Copyright © 2005 American Heart Association, Inc. All rights reserved. Gr...
متن کاملDiabetes and Alpha Lipoic Acid
Diabetes mellitus is a multi-faceted metabolic disorder where there is increased oxidative stress that contributes to the pathogenesis of this debilitating disease. This has prompted several investigations into the use of antioxidants as a complementary therapeutic approach. Alpha lipoic acid, a naturally occurring dithiol compound which plays an essential role in mitochondrial bioenergetic rea...
متن کاملAlpha-lipoic acid prevents endothelial dysfunction in obese rats via activation of AMP-activated protein kinase.
OBJECTIVE Lipid accumulation in vascular endothelial cells may play an important role in the pathogenesis of atherosclerosis in obese subjects. We showed previously that alpha-lipoic acid (ALA) activates AMP-activated protein kinase (AMPK) and reduces lipid accumulation in skeletal muscle of obese rats. Here, we investigated whether ALA improves endothelial dysfunction in obese rats by activati...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2019
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.2019.33.1_supplement.678.13